BRAND: Protak Scientific
Enzyme Indicators (EIs) are a major step forward in measuring the performance or efficacy of bio-decontamination cycles with vaporized hydrogen peroxide (VH2O2). It is an alternative technology to biological indicators that offers greater safety, speed, and profitability.
The indicator is based on an enzyme, thermostable Adenilate Kinase (tAK), which has a high tolerance to high temperatures and/or oxidizing chemical agents that would quickly inactivate most proteins. This enzyme has a predictable inactivation pattern, similar to the mortality rate of a spore population. Its presence and activity can be measured using a fast and sensitive luminescence test. These characteristics make tAK an ideal substitute marker for monitoring bio-decontamination processes.
Instant Results – The effectiveness of the biodecontamination process can be obtained in a few seconds, using a luminescence reader that provides RLU (Relative Light Units) data, which can be correlated with the logarithmic reduction achieved.
Accurate Data Capture – The luminometer provides quantifiable, linear data that provides the users with information substantially more valuable than the current BIs. EIs can act as early warning systems, enabling performance monitoring or threshold detection for cycle optimization.
Simple and easy to use – Enzyme indicators are simple and easy to use and can therefore be used regularly by technicians and users in both hospitals and pharmaceutical industries.
Audit Process Support – Validation with enzyme indicators provides the information needed to pass an audit process quickly and easily and meet regulatory scrutiny.
Reliability – EIs have a low level of variability between batches and therefore do not give false positive problems (rogue BIs).